Domestic refrigerators annually consume approximately 17,500 metric tons of traditional refrigerants such as Chlorofluorocarbon (CFC) and Hydroflourocarbon (HFC) which contribute to very high Ozone Depletion Potential (ODP) and Global Warming Potential (GWP). Good progress is being made with the phase out of CFC 22 from new equipment manufacture by replacing LPG since it possesses an environmentally friendly nature with no ODP. LPG is expected to results in comparable product efficiencies based on its characteristics. Therefore, this two types of refrigerants (LPG and CFC 22) to be examined using a modified domestic refrigerator in term of their performance characteristics parameters such as pressure and temperature at specified location at the refrigerator and the safety requirements while conducting the experiment. Based on the present work, it is indicate that the successful of using LPG as an alternative refrigerant to replace CFC 22 in domestic refrigerators is possible by getting LPG COP as 13 compared to 10 for CFC22

LPG consists mainly of propane (R-290) and butane (R-600), and LPG is available as a side product in local refineries. In Cuba for already several decades LPG is used as a drop-in refrigerant. LPG mixtures have composition of a commercial LPG mixture suitable as ‘drop-in’ replacement for R-12 was calculated crudely as 64% propane and 36% butane by mass. Liquefied petroleum gas (LPG) of 60% propane and 40% commercial butane has been tested as a drop in suitable for R 134a in a single evaporator domestic refrigerator with a total volume of 10 ft3